Not really, I feel like I've exhausted what I can get from having a higher sample size for the same terrible experimental methodology. If you want to run a double-blind trial on yourself I'd be interested.
Not really, I feel like I've exhausted what I can get from having a higher sample size for the same terrible experimental methodology. If you want to run a double-blind trial on yourself I'd be interested.
Gwern's written-up (in impressive detail) some blinded (double-blinded?) experiments he's done with 'nootropics' if you're interested in a detailed answer.
I know this is 3.5 years late, but FWIW, the effects of kanna compounds are perceptible for me within an hour of taking it – it's nothing like traditional SSRIs. The Zembrin website says fully effective within 1-2 days.
Not really, I feel like I've exhausted what I can get from having a higher sample size for the same terrible experimental methodology. If you want to run a double-blind trial on yourself I'd be interested.
Running a double-blind trial on yourself for a drug whose effects are meant to kick in after days or weeks seems difficult. How would you manage this?
As long as you don’t need the results quickly, just randomize in longer blocks of time (say, 2 weeks) rather than randomizing on a day-to-day level.
Gwern's written-up (in impressive detail) some blinded (double-blinded?) experiments he's done with 'nootropics' if you're interested in a detailed answer.
I know this is 3.5 years late, but FWIW, the effects of kanna compounds are perceptible for me within an hour of taking it – it's nothing like traditional SSRIs. The Zembrin website says fully effective within 1-2 days.
Makes sense! In that case you might want to edit the preregistration bit out of the Lorien page about Zembrin so people don't email you about it.